Selective Wee1 Inhibitors Led to Antitumor Activity In Vitro and Correlated with Myelosuppression
Author:
Affiliation:
1. EMD Serono, Billerica, Massachusetts 01821, United States
2. Merck Healthcare KGaA, 64293 Darmstadt, Germany
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.2c00481
Reference47 articles.
1. Targeting WEE1 Kinase in Cancer
2. A WEE1 family business: regulation of mitosis, cancer progression, and therapeutic target
3. Wee1 kinase as a target for cancer therapy
4. Discovery of ZN-c3, a Highly Potent and Selective Wee1 Inhibitor Undergoing Evaluation in Clinical Trials for the Treatment of Cancer
5. Abstract 4423: Antitumor activity of the novel oral highly selective Wee1 inhibitor Debio 0123
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