Synthesis and In Vivo Profiling of Desymmetrized Antimalarial Trioxolanes with Diverse Carbamate Side Chains-Reference-Cited by-同舟云学术

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Synthesis and In Vivo Profiling of Desymmetrized Antimalarial Trioxolanes with Diverse Carbamate Side Chains

Published:2024-09-05 Issue: Volume: Page:
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Klope Matthew T.¹,Tapia Cardona Juan A.¹²,Chen Jun¹,Gonciarz Ryan L.¹,Cheng Ke¹^ORCID,Jaishankar Priyadarshini¹,Kim Julie¹,Legac Jenny²,Rosenthal Philip J.²,Renslo Adam R.¹^ORCID

Affiliation:

1. Department of Pharmaceutical Chemistry, University of California, San Francisco, 600 16th Street, San Francisco, California 94158, United States

2. Department of Medicine, San Francisco General Hospital, University of California, San Francisco, California 94143, United States

Funder

Division of Microbiology and Infectious Diseases

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.4c00365

Reference21 articles.

1. World Health Organization (WHO). World Malaria Report 2023; WHO: Geneva, 2023.

2. Evolution of Partial Resistance to Artemisinins in Malaria Parasites in Uganda

3. Emergence, transmission dynamics and mechanisms of artemisinin partial resistance in malaria parasites in Africa

4. Artemisinin inspired synthetic endoperoxide drug candidates: Design, synthesis, and mechanism of action studies

5. The Structure−Activity Relationship of the Antimalarial Ozonide Arterolane (OZ277)

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