GSK6853, a Chemical Probe for Inhibition of the BRPF1 Bromodomain-Reference-Cited by-同舟云学术

GSK6853, a Chemical Probe for Inhibition of the BRPF1 Bromodomain

Published:2016-05-30 Issue:6 Volume:7 Page:552-557
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Bamborough Paul,Barnett Heather A.,Becher Isabelle¹,Bird Mark J.,Chung Chun-wa,Craggs Peter D.,Demont Emmanuel H.,Diallo Hawa,Fallon David J.²,Gordon Laurie J.,Grandi Paola¹,Hobbs Clare I.,Hooper-Greenhill Edward,Jones Emma J.,Law Robert P.²,Le Gall Armelle,Lugo David,Michon Anne-Marie¹,Mitchell Darren J.,Prinjha Rab K.,Sheppard Robert J.,Watson Allan J. B.²,Watson Robert J.

Affiliation:

1. Cellzome GmbH, GlaxoSmithKline, Meyerhofstrasse 1, 69117 Heidelberg, Germany

2. WestCHEM, Department of Pure and Applied Chemistry, University of Strathclyde, Thomas Graham Building, 295 Cathedral Street, Glasgow G1 1XL, U.K.

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.6b00092

Reference24 articles.

1. Histone Recognition and Large-Scale Structural Analysis of the Human Bromodomain Family

2. Suppression of inflammation by a synthetic histone mimic