Exploring N-Arylsulfonyl-l-proline Scaffold as a Platform for Potent and Selective αvβ1 Integrin Inhibitors-Reference-Cited by-同舟云学术

Exploring N-Arylsulfonyl-l-proline Scaffold as a Platform for Potent and Selective αvβ1 Integrin Inhibitors

Published:2016-09-02 Issue:10 Volume:7 Page:902-907
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Reed Nilgun Isik¹,Tang You-Zhi²³,McIntosh Joel²,Wu Yibing²,Molnar Kathleen S.²,Civitavecchia Annafelicia²,Sheppard Dean¹,DeGrado William F.²⁴,Jo Hyunil²

Affiliation:

1. Department of Medicine, University of California−San Francisco, San Francisco, California 94153, United States

2. Department of Pharmaceutical Chemistry, University of California−San Francisco, San Francisco, California 94158, United States

3. College of Veterinary Medicine, South China Agricultural University, Guangdong 510642, China

4. Cardiovascular Research Institute, University of California−San Francisco, San Francisco, California 94158, United States

Funder

U.S. Department of Health and Human Services

China Scholarship Council

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.6b00196

Reference20 articles.

1. Integrins: Versatility, modulation, and signaling in cell adhesion

2. Integrins

3. Integrins as therapeutic targets

4. Pharmacological treatment of idiopathic pulmonary fibrosis: an update

5. Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs

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