Discovery of Irbesartan Derivatives as BLT2 Agonists by Virtual Screening-Reference-Cited by-同舟云学术

Discovery of Irbesartan Derivatives as BLT2 Agonists by Virtual Screening

Published:2021-07-06 Issue:8 Volume:12 Page:1261-1266
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Hernandez-Olmos Victor¹,Heering Jan¹^ORCID,Bischoff-Kont Iris²,Kaps Alexander¹³,Rajkumar Rinusha¹³,Liu Ting¹³,Fürst Robert²,Steinhilber Dieter¹³,Proschak Ewgenij¹³^ORCID

Affiliation:

1. Fraunhofer Institute for Translational Medicine and Phamacology ITMP, Theodor-Stern-Kai 7, 60596 Frankfurt am Main, Germany

2. Institute of Pharmaceutical Biology, Goethe University Frankfurt, Max-von-Laue-Str. 9, 60438 Frankfurt am Main, Germany

3. Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, Max-von-Laue-Str. 9, 60438 Frankfurt am Main, Germany

Funder

Deutsche Forschungsgemeinschaft

Landes-Offensive zur Entwicklung Wissenschaftlich-Ã¶konomischer Exzellenz

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.1c00240

Reference15 articles.

1. A Second Leukotriene B4 Receptor, Blt2

2. Two distinct leukotriene B4 receptors, BLT1 and BLT2

3. Leukotriene B4 receptors: Novel roles in immunological regulations

4. 12(S)-hydroxyheptadeca-5Z, 8E, 10E–trienoic acid is a natural ligand for leukotriene B4 receptor 2

5. A synthetic leukotriene B4 receptor type 2 agonist accelerates the cutaneous wound healing process in diabetic rats by indirect stimulation of fibroblasts and direct stimulation of keratinocytes

Cited by 6 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Automated design of multi-target ligands by generative deep learning;Nature Communications;2024-09-11

2. Development of a Potent and Selective G2A (GPR132) Agonist;Journal of Medicinal Chemistry;2024-06-25

3. General Installation of (4H)-Imidazolone cis-Amide Bioisosteres Along the Peptide Backbone;Journal of the American Chemical Society;2024-04-17

4. Novel Synthesis and Characterization of Irbesartan Derivative an Anti‐Hypertensive Active Pharmaceutical Ingredient (API);Macromolecular Symposia;2024-02

5. Thioimidates provide general access to thioamide, amidine, and imidazolone peptide-bond isosteres;Methods in Enzymology;2024