Design and Catalyzed Activation of Mycophenolic Acid Prodrugs-Reference-Cited by-同舟云学术

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Design and Catalyzed Activation of Mycophenolic Acid Prodrugs

Published:2021-04-08 Issue:5 Volume:12 Page:812-816
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Plunk Michael A.¹,Quintana Jeremy M.¹,Darden Carly M.²,Lawrence Michael C.²³,Naziruddin Bashoo²⁴,Kane Robert R.¹²^ORCID

Affiliation:

1. Department of Chemistry and Biochemistry, Baylor University, Waco, Texas 76706, United States

2. Institute of Biomedical Studies, Baylor University, Waco, Texas 76706, United States

3. Islet Cell Laboratory, Baylor Scott and White Research Institute, Dallas, Texas 75204, United States

4. Baylor Simmons Transplant Institute, Baylor University Medical Center, Dallas, Texas 75204, United States

Funder

National Institute of Diabetes and Digestive and Kidney Diseases

Baylor University

Juvenile Diabetes Research Foundation

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.1c00079

Reference31 articles.

1. A Novel Cyclohexene Derivative, Ethyl (6R)-6-[N-(2-Chloro-4-fluorophenyl)sulfamoyl]cyclohex-1-ene-1-carboxylate (TAK-242), Selectively Inhibits Toll-Like Receptor 4-Mediated Cytokine Production through Suppression of Intracellular Signaling

2. Discovery of Novel and Potent Small-Molecule Inhibitors of NO and Cytokine Production as Antisepsis Agents: Synthesis and Biological Activity of Alkyl 6-(N-Substituted sulfamoyl)cyclohex-1-ene-1-carboxylate

3. Ex-vivo generation of drug-eluting islets improves transplant outcomes by inhibiting TLR4-Mediated NFkB upregulation

4. Design and Catalyzed Activation of Tak-242 Prodrugs for Localized Inhibition of TLR4-Induced Inflammation

5. The use of mycophenolate mofetil in transplant recipients

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2. Ganodermanontriol Suppresses the Progression of Lung Adenocarcinoma by Activating CES2 to Enhance the Metabolism of Mycophenolate Mofetil;Journal of Microbiology and Biotechnology;2023-10-01

3. In Cellulo Bioorthogonal Catalysis by Encapsulated AuPd Nanoalloys: Overcoming Intracellular Deactivation;Nano Letters;2023-01-17

4. Solid–liquid phase equilibrium of mycophenolic acid in 14 mono-solvents: Measurements, correlation, solvent effect and molecular simulation;Journal of Molecular Liquids;2022-11

5. An Overview of Natural and Synthetic Phthalides Involved in Cancer Studies: Past, Present, and Future;ChemistrySelect;2022-10-04

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