Discovery of Novel and Potent Small-Molecule Inhibitors of NO and Cytokine Production as Antisepsis Agents: Synthesis and Biological Activity of Alkyl 6-(N-Substituted sulfamoyl)cyclohex-1-ene-1-carboxylate-Reference-Cited by-同舟云学术

Discovery of Novel and Potent Small-Molecule Inhibitors of NO and Cytokine Production as Antisepsis Agents: Synthesis and Biological Activity of Alkyl 6-(N-Substituted sulfamoyl)cyclohex-1-ene-1-carboxylate

Published:2005-10-14 Issue:23 Volume:48 Page:7457-7467
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Yamada Masami¹,Ichikawa Takashi¹,Ii Masayuki¹,Sunamoto Mie¹,Itoh Katsumi¹,Tamura Norikazu¹,Kitazaki Tomoyuki¹

Affiliation:

1. Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, 17-85, Jusohonmachi-2-chome, Yodogawa-ku, Osaka 532-8686, Japan

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm050623t

Reference37 articles.

1. Case 20-1993

2. The systemic inflammatory response syndrome: definitions and aetiology

3. The Pathophysiology and Treatment of Sepsis

Cited by 97 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Peripheral inflammation triggering central anxiety through the hippocampal glutamate metabolized receptor 1;CNS Neuroscience & Therapeutics;2024-04

2. Intracerebral hemorrhage‐induced brain injury in mice: The role of peroxiredoxin 2‐Toll‐like receptor 4 inflammatory axis;CNS Neuroscience & Therapeutics;2024-03

3. Determining zebrafish dorsal organizer size by a negative feedback loop between canonical/non-canonical Wnts and Tlr4/NFκB;Nature Communications;2023-11-08

4. Inhibition of TLR4 signalling to dampen joint inflammation in osteoarthritis;Rheumatology;2023-10-03

5. Targeting Toll-like receptor-driven systemic inflammation by engineering an innate structural fold into drugs;Nature Communications;2023-09-29