Impact of Minor Structural Modifications on Properties of a Series of mTOR Inhibitors-Reference-Cited by-同舟云学术

Impact of Minor Structural Modifications on Properties of a Series of mTOR Inhibitors

Published:2019-10-04 Issue:11 Volume:10 Page:1561-1567
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Ouvry Gilles¹^ORCID,Clary Laurence¹,Tomas Loïc¹,Aurelly Michèle¹,Bonnary Laetitia¹,Borde Emilie¹,Bouix-Peter Claire¹,Chantalat Laurent¹,Defoin-Platel Claire¹,Deret Sophie¹,Forissier Mathieu¹,Harris Craig S.¹,Isabet Tatiana²,Lamy Laurent¹,Luzy Anne-Pascale¹,Pascau Jonathan¹,Soulet Catherine¹,Taddei Alessandro¹,Taquet Nathalie¹,Thoreau Etienne¹,Varvier Emeric¹,Vial Emmanuel¹,Hennequin Laurent F.¹

Affiliation:

1. Nestlé Skin Health R&D, 2400 Route des colles, BP 87, 06902 Sophia-Antipolis Cedex, France

2. Synchrotron Soleil, L’Orme des Merisiers, Saint-Aubin - BP 48, 91192 Gif-sur-Yvette Cedex, France

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.9b00401

Reference32 articles.

1. Recent advances in the discovery of small-molecule ATP competitive mTOR inhibitors: a patent review

2. Recent advances in targeting mTOR signaling pathway using small molecule inhibitors

3. mTOR signaling cascade in psoriatic disease: Double kinase mtor inhibitor a novel therapeutic target

4. Phosphoinositide-3 Kinase/Protein Kinase-B/Mammalian Target of Rapamycin Pathway in Psoriasis Pathogenesis. A Potential Therapeutic Target?

5. Combination of everolimus and tacrolimus: a potentially effective regimen for recalcitrant psoriasis

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