Novel Small Molecule-Derived, Highly Selective Substrates for Fibroblast Activation Protein (FAP)-Reference-Cited by-同舟云学术

Novel Small Molecule-Derived, Highly Selective Substrates for Fibroblast Activation Protein (FAP)

Published:2019-07-09 Issue:8 Volume:10 Page:1173-1179
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

De Decker An¹,Vliegen Gwendolyn²,Van Rompaey Dries¹,Peeraer Anke¹,Bracke An²,Verckist Line³,Jansen Koen¹,Geiss-Friedlander Ruth⁴,Augustyns Koen¹^ORCID,De Winter Hans¹^ORCID,De Meester Ingrid²,Lambeir Anne-Marie²,Van der Veken Pieter¹^ORCID

Affiliation:

1. Laboratory of Medicinal Chemistry (UAMC), Department of Pharmaceutical Sciences, University of Antwerp, Universiteitsplein 1, B-2610 Wilrijk (Antwerp), Belgium

2. Laboratory of Medical Biochemistry, Department of Pharmaceutical Sciences, University of Antwerp, Universiteitsplein 1, B-2610 Wilrijk (Antwerp), Belgium

3. Laboratory of Cell Biology and Histology, Department of Veterinary Sciences, University of Antwerp, Universiteitsplein 1, B-2610 Wilrijk (Antwerp), Belgium

4. Institut für Molekularbiologie, Universitätsmedizin Göttingen, Humboldtallee 23, D-37073 Göttingen, Germany

Funder

Deutsche Forschungsgemeinschaft

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.9b00191

Reference28 articles.

1. Fibroblast Activation Protein, a Dual Specificity Serine Protease Expressed in Reactive Human Tumor Stromal Fibroblasts

2. Understanding fibroblast activation protein (FAP): Substrates, activities, expression and targeting for cancer therapy