Deoxyfluorination of Ketones with Sulfur Tetrafluoride (SF<sub>4</sub>) and Dialkylamines in Continuous Flow Mode-Reference-Cited by-同舟云学术

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Deoxyfluorination of Ketones with Sulfur Tetrafluoride (SF₄) and Dialkylamines in Continuous Flow Mode

Published:2024-07-08 Issue:7 Volume:28 Page:2919-2927
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Polterauer Dominik¹²^ORCID,Wagschal Simon³^ORCID,Bersier Michael³,Bovino Clara³,Roberge Dominique M.³,Hone Christopher A.¹²^ORCID,Kappe C. Oliver¹²^ORCID

Affiliation:

1. Center for Continuous Flow Synthesis and Processing (CCFLOW), Research Center Pharmaceutical Engineering GmbH (RCPE), Inffeldgasse 13, Graz 8010, Austria

2. Institute of Chemistry, University of Graz, NAWI Graz, Heinrichstrasse 28, Graz A-8010, Austria

3. Advanced Chemistry Technologies, Lonza AG, Visp CH-3930, Switzerland

Funder

?sterreichische Forschungsf?rderungsgesellschaft

Steirische Wirtschaftsf?rderungsgesellschaft

Bundesministerium f?r Digitalisierung und Wirtschaftsstandort

Bundesministerium f?r Klimaschutz, Umwelt, Energie, Mobilit?t, Innovation und Technologie

Land Steiermark

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.4c00180

Reference72 articles.

1. Late-Stage Fluorination: Fancy Novelty or Useful Tool?

2. Applications of Fluorine in Medicinal Chemistry

3. Fluorine in Pharmaceuticals: Looking Beyond Intuition

4. Understanding organofluorine chemistry. An introduction to the C–F bond

5. FDA-Approved Fluorinated Heterocyclic Drugs from 2016 to 2022

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