Tetrazole as a Replacement of the Electrophilic Group in Characteristic Prolyl Oligopeptidase Inhibitors-Reference-Cited by-同舟云学术

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Tetrazole as a Replacement of the Electrophilic Group in Characteristic Prolyl Oligopeptidase Inhibitors

Published:2019-11-11 Issue:12 Volume:10 Page:1635-1640
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Kilpeläinen Tommi P.¹,Tyni Jonna K.²,Lahtela-Kakkonen Maija K.²^ORCID,Eteläinen Tony S.¹,Myöhänen Timo T.¹,Wallén Erik A. A.³^ORCID

Affiliation:

1. Drug Research Program, Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki, P.O. Box 56, 00014 Helsinki, Finland

2. School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, Yliopistonranta 1C, 70211 Kuopio, Finland

3. Drug Research Program, Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki, P.O. Box 56, 00014 Helsinki, Finland

Funder

Academy of Finland

Jane ja Aatos Erkon S??ti?

It?-Suomen Yliopisto

Business Finland

HiLIFE

Sigrid Juselius Foundation

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.9b00394

Reference29 articles.

1. On the role of prolyl oligopeptidase in health and disease

2. Distribution of Immunoreactive Prolyl Oligopeptidase in Human and Rat Brain

3. Characterization of proline endopeptidase from skeletal muscle

4. Distribution of Prolyl Oligopeptidase in Human Peripheral Tissues and Body Fluids

5. Distribution of prolyl oligopeptidase in the mouse whole-body sections and peripheral tissues

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1. Synthesis, biological evaluation, and molecular modelling of substituted thiazolyl thiourea derivatives: A new class of prolyl oligopeptidase inhibitors;International Journal of Biological Macromolecules;2024-08

2. Tetrazole derivatives in the management of neurological disorders: Recent advances on synthesis and pharmacological aspects;European Journal of Medicinal Chemistry;2024-05

3. Catalytic Tetrazole Synthesis via [3+2] Cycloaddition of NaN₃ to Organonitriles Promoted by Co(II)-complex: Isolation and Characterization of a Co(II)-diazido Intermediate;ACS Omega;2024-04-29

4. 5-Aminothiazoles Reveal a New Ligand-Binding Site on Prolyl Oligopeptidase Which is Important for Modulation of Its Protein–Protein Interaction-Derived Functions;Journal of Medicinal Chemistry;2024-03-28

5. Nonpeptidic Oxazole-Based Prolyl Oligopeptidase Ligands with Disease-Modifying Effects on α-Synuclein Mouse Models of Parkinson’s Disease;Journal of Medicinal Chemistry;2023-05-29

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