Discovery of Axelopran (TD-1211): A Peripherally Restricted μ-Opioid Receptor Antagonist-Reference-Cited by-同舟云学术

Discovery of Axelopran (TD-1211): A Peripherally Restricted μ-Opioid Receptor Antagonist

Published:2019-11-26 Issue:12 Volume:10 Page:1641-1647
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Long Daniel D.¹^ORCID,Armstrong Scott R.¹,Beattie David T.¹,Campbell Christina B.¹,Church Timothy J.¹,Colson Pierre-Jean¹,Dalziel Sean M.¹,Jacobsen John R.¹,Jiang Lan¹,Obedencio Glenmar P.¹,Rapta Miroslav¹,Saito Daisuke¹,Stergiades Ioanna¹,Tsuruda Pamela R.¹,Van Dyke Priscilla M.¹,Vickery Ross G.¹

Affiliation:

1. Theravance Biopharma US, Inc., 901 Gateway Blvd., South San Francisco, California 94080, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.9b00406

Reference30 articles.

1. Clinical Guidelines for the Use of Chronic Opioid Therapy in Chronic Noncancer Pain

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4. Current concepts in the management of opioid-induced constipation

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