Discovery of ABBV/GLPG-3221, a Potent Corrector of CFTR for the Treatment of Cystic Fibrosis
Author:
Affiliation:
1. Research and Development, AbbVie, Inc., 1 North Waukegan Road, North Chicago, Illinois 60064, United States
Funder
AbbVie
Galapagos
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.9b00377
Reference28 articles.
1. Cystic fibrosis genetics: from molecular understanding to clinical application
2. Identification of the Cystic Fibrosis Gene: Genetic Analysis
3. Molecular mechanisms of CFTR chloride channel dysfunction in cystic fibrosis
4. CYSTIC FIBROSIS: GENOTYPIC AND PHENOTYPIC VARIATIONS
5. Folding and Misfolding of Human Membrane Proteins in Health and Disease: From Single Molecules to Cellular Proteostasis
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