Scaffold Hopping-Driven Optimization of 4-(Quinazolin-4-yl)-3,4-dihydroquinoxalin-2(1H)-ones as Novel Tubulin Inhibitors-Reference-Cited by-同舟云学术

Scaffold Hopping-Driven Optimization of 4-(Quinazolin-4-yl)-3,4-dihydroquinoxalin-2(1H)-ones as Novel Tubulin Inhibitors

Published:2019-12-30 Issue:1 Volume:11 Page:83-89
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Jiang Li¹,Goto Masuo²^ORCID,Zhu Dong-Qing¹,Hsu Pei-Ling²,Li Kang-Po²,Cui Mutian¹,He Xiaoyang³,Morris-Natschke Susan Lynne²,Lee Kuo-Hsiung²⁴^ORCID,Xie Lan¹²

Affiliation:

1. Beijing Institute of Pharmacology and Toxicology, 27 Tai-Ping Road, Beijing 100850, China

2. Natural Products Research Laboratories, UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina 27599, United States

3. Beijing Institute of Radiation Medicine, 27 Tai-Ping Road, Beijing 100850, China

4. Chinese Medicine Research and Development Center, China Medical University and Hospital, Taichung, Taiwan

Funder

National Cancer Institute

National Natural Science Foundation of China

Eshelman Institute for Innovation, University of North Carolina

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.9b00352