Discovery of 2,4-1H-Imidazole Carboxamides as Potent and Selective TAK1 Inhibitors-Reference-Cited by-同舟云学术

Discovery of 2,4-1H-Imidazole Carboxamides as Potent and Selective TAK1 Inhibitors

Published:2021-03-03 Issue:4 Volume:12 Page:555-562
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Veerman Johan J. N.¹^ORCID,Bruseker Yorik B.²,Damen Eddy²,Heijne Erik H.²^ORCID,van Bruggen Wendy²,Hekking Koen F. W.²,Winkel Rob²,Hupp Christopher D.³,Keefe Anthony D.³,Liu Julie⁴,Thomson Heather A.³,Zhang Ying³,Cuozzo John W.³^ORCID,McRiner Andrew J.³,Mulvihill Mark J.⁵,van Rijnsbergen Peter²,Zech Birgit⁶,Renzetti Louis M.⁷,Babiss Lee⁸,Müller Gerhard⁶

Affiliation:

1. ZoBio BV, J.H. Oortweg 19, 2333 CH Leiden, The Netherlands

2. Mercachem BV, Department of Medicinal Chemistry, Kerkenbos 1013, 6546 BB Nijmegen, The Netherlands

3. X-Chem, Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States

4. Civetta Therapeutics, 10 Wilson Road, Cambridge, Massachusetts 02138, United States

5. HiberCell Inc., New York, New York 10019, United States

6. AnavoTherapeutics BV, J.H. Oortweg 19, 2333 CH Leiden, The Netherlands

7. Bridge Medicines LLC, New York, New York 10017, United States

8. Wilmington, North Carolina 28405, United States

Publisher

American Chemical Society (ACS)

Subject