Screening Ultra-Large Encoded Compound Libraries Leads to Novel Protein–Ligand Interactions and High Selectivity-Reference-Cited by-同舟云学术

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Screening Ultra-Large Encoded Compound Libraries Leads to Novel Protein–Ligand Interactions and High Selectivity

Published:2024-01-10 Issue:2 Volume:67 Page:864-884
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Collie Gavin W.¹^ORCID,Clark Matthew A.²,Keefe Anthony D.²,Madin Andrew¹,Read Jon A.¹,Rivers Emma L.¹,Zhang Ying²

Affiliation:

1. AstraZeneca, Cambridge CB2 0AA, U.K.

2. X-Chem, Inc., Waltham, Massachusetts 02453, United States

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c01861

Reference158 articles.

1. Small-Molecule Lead-Finding Trends across the Roche and Genentech Research Organizations

2. Lead Generation Based on Compound Collection Screening

3. The Design and Application of Target-Focused Compound Libraries

4. Trends in Kinase Selectivity: Insights for Target Class-Focused Library Screening

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Hit me with your best shot: Integrated hit discovery for the next generation of drug targets;Drug Discovery Today;2024-10

2. Building Block-Centric Approach to DNA-Encoded Library Design;Journal of Chemical Information and Modeling;2024-06-11

3. Data-oriented protein kinase drug discovery;European Journal of Medicinal Chemistry;2024-05

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