Synthesis of Resolvin E1 and Its Conformationally Restricted Cyclopropane Congeners with Potent Anti-Inflammatory Effect-Reference-Cited by-同舟云学术

Synthesis of Resolvin E1 and Its Conformationally Restricted Cyclopropane Congeners with Potent Anti-Inflammatory Effect

Published:2021-01-21 Issue:2 Volume:12 Page:256-261
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Ishimura Kohei,Fukuda Hayato¹^ORCID,Fujiwara Koichi,Muromoto Ryuta,Hirashima Koki,Murakami Yuto,Watanabe Mizuki^ORCID,Ishihara Jun¹^ORCID,Matsuda Tadashi,Shuto Satoshi^ORCID

Affiliation:

1. Graduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-Machi, Nagasaki 852-8521, Japan

Funder

Takeda Science Foundation

Japan Agency for Medical Research and Development

Japan Society for the Promotion of Science

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.0c00639

Reference39 articles.

1. Resolvins and Protectins in Inflammation Resolution

2. Pro-resolving lipid mediators are leads for resolution physiology

3. Resolvin E1 Improves Mitochondrial Function in Human Alveolar Epithelial Cells during Severe Inflammation

4. Resolvin E1 is a pro-repair molecule that promotes intestinal epithelial wound healing

5. Metabolic Inactivation of Resolvin E1 and Stabilization of Its Anti-inflammatory Actions

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