Strategic Incorporation of Polarity in Heme-Displacing Inhibitors of Indoleamine-2,3-dioxygenase-1 (IDO1)
Author:
Affiliation:
1. Proteros biostructures GmbH, 82152 Martinsried, Germany
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.0c00010
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1. The Combined Effects of Tryptophan Starvation and Tryptophan Catabolites Down-Regulate T Cell Receptor ζ-Chain and Induce a Regulatory Phenotype in Naive T Cells
2. Discovery of IDO1 Inhibitors: From Bench to Bedside
3. An expanding range of targets for kynurenine metabolites of tryptophan
4. Indoleamine 2,3 dioxygenase and metabolic control of immune responses
5. Indoleamine 2,3-dioxygenase and tumor-induced tolerance
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