Facile Synthesis of Aminomethyl Phosphinate Esters as Serine Protease Inhibitors with Primed Site Interaction-Reference-Cited by-同舟云学术

Facile Synthesis of Aminomethyl Phosphinate Esters as Serine Protease Inhibitors with Primed Site Interaction

Published:2020-08-10 Issue:9 Volume:11 Page:1739-1744
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Kahler Jan Pascal¹,Lenders Stijn¹^ORCID,van de Plassche Merel A. T.¹,Verhelst Steven H. L.¹²^ORCID

Affiliation:

1. Laboratory of Chemical Biology, Department of Cellular and Molecular Medicine, KU Leuven − University of Leuven, Herestraat 49 Box 802, 3000 Leuven, Belgium

2. AG Chemical Proteomics, Leibniz Institute for Analytical Sciences − ISAS, Otto-Hahn-Str. 6b, 44227 Dortmund, Germany

Funder

Bundesministerium f?r Bildung und Forschung

Fonds Wetenschappelijk Onderzoek

Ministerium f?r Kultur und Wissenschaft des Landes Nordrhein-Westfalen

Berlin City

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.0c00284

Reference31 articles.

1. Application of a chemical probe to detect neutrophil elastase activation during inflammatory bowel disease

2. The Neutrophil in Chronic Obstructive Pulmonary Disease. Too Little, Too Late or Too Much, Too Soon?

3. Neutrophil Elastase (NE) and NE Inhibitors: Canonical and Noncanonical Functions in Lung Chronic Inflammatory Diseases (Cystic Fibrosis and Chronic Obstructive Pulmonary Disease)

4. Neutrophil Extracellular Traps Kill Bacteria

5. Proteases in Human Diseases

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