Small Molecule Fluorescent Ligands for the Atypical Chemokine Receptor 3 (ACKR3)-Reference-Cited by-同舟云学术

Small Molecule Fluorescent Ligands for the Atypical Chemokine Receptor 3 (ACKR3)

Published:2023-12-08 Issue:1 Volume:15 Page:143-148
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Dekkers Sebastian¹,Comez Dehan²³,Karsai Noemi²³,Arimont-Segura Marta⁴,Canals Meritxell²³^ORCID,Caspar Birgit²³,de Graaf Chris⁴,Kilpatrick Laura E.¹²^ORCID,Leurs Rob⁴^ORCID,Kellam Barrie¹²^ORCID,Hill Stephen J.²³^ORCID,Briddon Stephen J.²³,Stocks Michael J.¹^ORCID

Affiliation:

1. Biodiscovery Institute, School of Pharmacy, University of Nottingham, Nottingham NG7 2RD, United Kingdom

2. Centre of Membrane Proteins and Receptors, University of Birmingham and University of Nottingham, The Midlands NG7 2UH, United Kingdom

3. Division of Physiology, Pharmacology & Neuroscience, Medical School, University of Nottingham, Nottingham NG7 2UH, U.K.

4. Division of Medicinal Chemistry, Amsterdam Institute of Molecular and Life Sciences (AIMMS), Faculty of Science, Vrije Universiteit Amsterdam, De Boelelaan 1108, Amsterdam 1081 HZ, The Netherlands

Funder

Medical Research Council

University of Nottingham

H2020 Marie Sklodowska-Curie Actions

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.3c00469

Reference27 articles.

1. CXCR7 heterodimerizes with CXCR4 and regulates CXCL12-mediated G protein signaling

2. CXCR7 Functions as a Scavenger for CXCL12 and CXCL11

3. -arrestin- but not G protein-mediated signaling by the "decoy" receptor CXCR7

4. Expression of stromal cell-derived factor-1 receptors CXCR4 and CXCR7 on circulating platelets of patients with acute coronary syndrome and association with left ventricular functional recovery

5. Relative survival potential of platelets is associated with platelet CXCR4/CXCR7 surface exposure and functional recovery following STEMI

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