Novel Small-Molecule Atypical Chemokine Receptor 3 Agonists: Design, Synthesis, and Pharmacological Evaluation for Antiplatelet Therapy-Reference-Cited by-同舟云学术

Novel Small-Molecule Atypical Chemokine Receptor 3 Agonists: Design, Synthesis, and Pharmacological Evaluation for Antiplatelet Therapy

Published:2024-08-08 Issue:16 Volume:67 Page:14553-14573
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Bayrak Alp¹^ORCID,Szpakowska Martyna²^ORCID,Dicenta-Baunach Valerie³^ORCID,Counson Manuel²,Rasch Alexander¹,Rohlfing Anne-Katrin³,Chevigné Andy²^ORCID,Gawaz Meinrad³,Laufer Stefan A.²⁴⁵^ORCID,Pillaiyar Thanigaimalai¹⁴^ORCID

Affiliation:

1. Institute of Pharmacy, Pharmaceutical/Medicinal Chemistry, Eberhard Karls University Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany

2. Department of Infection and Immunity, Immuno-Pharmacology and Interactomics, Luxembourg Institute of Health (LIH), L-4354 Esch-sur-Alzette, Luxembourg

3. Department of Internal Medicine III, Cardiology and Angiology, University Hospital Tübingen, Otfried-Müller-Strasse 10, 72076 Tübingen, Germany

4. Tübingen Center for Academic Drug Discovery (TüCAD2), Auf der Morgenstelle 8, 72076 Tübingen, Germany

5. iFIT Cluster of Excellence (EXC 2180) “Image-guided and Functionally Instructed Tumor Therapies”, Eberhard Karls University Tübingen, 72076 Tübingen, Germany

Funder

Bundesministerium für Bildung und Forschung

Fonds National de la Recherche Luxembourg

Deutsche Forschungsgemeinschaft

Fonds De La Recherche Scientifique - FNRS

University of Tübingen

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.4c01371

Reference48 articles.

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3. Clinical significance of chemokine receptor antagonists

4. Structural Analysis of Chemokine Receptor–Ligand Interactions

5. The Chemokine Superfamily Revisited