MDM2 Antagonist Idasanutlin Reduces HDAC1/2 Abundance and Corepressor Partners but Not HDAC3
Author:
Affiliation:
1. Leicester Institute of Structural and Chemical Biology, School of Chemistry, University of Leicester, Leicester LE1 7RH, United Kingdom
2. Department of Molecular and Cell Biology, University of Leicester, Leicester LE1 7RH, United Kingdom
Funder
Engineering and Physical Sciences Research Council
Medical Research Council
Biotechnology and Biological Sciences Research Council
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.3c00449
Reference27 articles.
1. Thirty Years of HDAC Inhibitors: 2020 Insight and Hindsight
2. Erasers of Histone Acetylation: The Histone Deacetylase Enzymes
3. Targeting Class I Histone Deacetylases in a “Complex” Environment
4. Selective Inhibition of HDAC1 and HDAC2 as a Potential Therapeutic Option for B-ALL
5. Histone deacetylase 3 as a novel therapeutic target in multiple myeloma
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