Radiosynthesis and Evaluation of [11C]HD-800, a High Affinity Brain Penetrant PET Tracer for Imaging Microtubules-Reference-Cited by-同舟云学术

Radiosynthesis and Evaluation of [11C]HD-800, a High Affinity Brain Penetrant PET Tracer for Imaging Microtubules

Published:2018-04-30 Issue:5 Volume:9 Page:452-456
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Solingapuram Sai Kiran Kumar¹,Prabhakaran Jaya²³,Ramanathan Gayathri¹,Rideout Stephanie¹,Whitlow Christopher¹,Mintz Akiva⁴,Mann J. John²³⁴,Kumar J. S. Dileep²

Affiliation:

1. Department of Radiology, Wake Forest School of Medicine, Winston Salem, North Carolina, United States

2. Molecular Imaging and Neuropathology Division, New York State Psychiatric Institute, New York, United States

3. Department of Psychiatry, Columbia University Medical Center, New York, United States

4. Department of Radiology, Columbia University Medical Center, New York, United States

Funder

National Center for Advancing Translational Sciences

Diane Goldberg Foundation

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.8b00060

Reference29 articles.

1. The tubulin code: Molecular components, readout mechanisms, and functions

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3. The mechanics of microtubule networks in cell division

4. Molecules in mammalian brain that interact with the colchicine site on tubulin.

5. Microtubule-Targeting Agents Enter the Central Nervous System (CNS): Double-edged Swords for Treating CNS Injury and Disease

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