Discovery of TD-0212, an Orally Active Dual Pharmacology AT1 Antagonist and Neprilysin Inhibitor (ARNI)-Reference-Cited by-同舟云学术

Discovery of TD-0212, an Orally Active Dual Pharmacology AT1 Antagonist and Neprilysin Inhibitor (ARNI)

Published:2018-12-03 Issue:1 Volume:10 Page:86-91
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

McKinnell R. Murray¹^ORCID,Fatheree Paul¹,Choi Seok-Ki¹,Gendron Roland¹,Jendza Keith¹,Olson Blair Brooke¹,Budman Joe¹,Hill Craig M.¹,Hegde Laxminarayan G.¹,Yu Cecile¹,McConn Donavon¹,Hegde Sharath S.¹,Marquess Daniel G.¹,Klein Uwe¹

Affiliation:

1. Theravance Biopharma US Inc., 901 Gateway Boulevard, South San Francisco, California 94080, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.8b00462

Reference23 articles.

1. Angiotensin II and the Heart

2. Structural Basis for Ligand Recognition and Functional Selectivity at Angiotensin Receptor

3. Angiotensin Receptor Blockers: Current Status and Future Prospects

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