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Structural Basis for Ligand Recognition and Functional Selectivity at Angiotensin Receptor

  • Published:2015-12 Issue:49 Volume:290 Page:29127-29139
  • ISSN:0021-9258
  • Container-title:Journal of Biological Chemistry
  • language:en
  • Short-container-title:Journal of Biological Chemistry

Author:

Zhang Haitao,Unal Hamiyet,Desnoyer Russell,Han Gye Won,Patel Nilkanth,Katritch Vsevolod,Karnik Sadashiva S.,Cherezov Vadim,Stevens Raymond C.

Funder

National Institute of General Medical Sciences

National Heart, Lung, and Blood Institute

National Cancer Institute

U.S. Department of Energy—Office of Science

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference43 articles.

1. Drugs targeting the renin-angiotensin-aldosterone system;Zaman;Nat. Rev. Drug Discov,2002

2. Structural determinants for binding, activation, and functional selectivity of the angiotensin AT1 receptor;Balakumar;J. Mol. Endocrinol,2014

3. International union of pharmacology. XXIII. The angiotensin II receptors;de Gasparo;Pharmacol. Rev,2000

4. The angiotensin II AT1 receptor structure-activity correlations in the light of rhodopsin structure;Oliveira;Physiol. Rev,2007

5. Angiotensin II receptor antagonists;Burnier;Lancet,2000
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