Structure-Guided Design and Initial Studies of a Bifunctional MEK/PI3K Inhibitor (ST-168)
Author:
Affiliation:
1. Center for Molecular Imaging, ‡Department of Radiology, §Departments of Chemical and Biomedical Engineering, and ∥Department of Ophthalmology and Visual Sciences, The University of Michigan Medical School, Ann Arbor, Michigan 48109, United States
Funder
National Cancer Institute
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.7b00111
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1. Targeting PI3K signalling in cancer: opportunities, challenges and limitations
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