The emerging mechanisms of isoform-specific PI3K signalling-Reference-Cited by-同舟云学术

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The emerging mechanisms of isoform-specific PI3K signalling

Published:2010-04-09 Issue:5 Volume:11 Page:329-341
ISSN:1471-0072
Container-title:Nature Reviews Molecular Cell Biology
language:en
Short-container-title:Nat Rev Mol Cell Biol

Author:

Vanhaesebroeck Bart,Guillermet-Guibert Julie,Graupera Mariona,Bilanges Benoit

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology

Link

http://www.nature.com/articles/nrm2882.pdf

Reference175 articles.

1. Kok, K., Geering, B. & Vanhaesebroeck, B. Regulation of phosphoinositide 3-kinase expression in health and disease. Trends Biochem. Sci. 34, 115–127 (2009).

2. Vanhaesebroeck, B., Leevers, S. J., Panayotou, G. & Waterfield, M. D. Phosphoinositide 3-kinases: a conserved family of signal transducers. Trends Biochem. Sci. 22, 267–272 (1997).

3. Vanhaesebroeck, B., Ali, K., Bilancio, A., Geering, B. & Foukas, L. C. Signalling by PI3K isoforms: insights from gene-targeted mice. Trends Biochem. Sci. 30, 194–204 (2005).

4. Chamberlain, M. D. et al. Disrupted RabGAP function of the p85 subunit of phosphatidylinositol 3-kinase results in cell transformation. J. Biol. Chem. 283, 15861–15868 (2008).

5. Vanhaesebroeck, B. et al. P110δ, a novel phosphoinositide 3-kinase in leukocytes. Proc. Natl Acad. Sci. USA 94, 4330–4335 (1997).

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