Synthesis and in Vivo Antitumor Evaluation of 2-Methoxyestradiol 3-Phosphate, 17-Phosphate, and 3,17-Diphosphate-Reference-Cited by-同舟云学术

Synthesis and in Vivo Antitumor Evaluation of 2-Methoxyestradiol 3-Phosphate, 17-Phosphate, and 3,17-Diphosphate

Published:2007-12-01 Issue:26 Volume:50 Page:6700-6705
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Edsall Allison B.¹,Agoston Gregory E.¹,Treston Anthony M.¹,Plum Stacy M.¹,McClanahan Robert H.¹,Lu Tian-Sheng¹,Song Wei¹,Cushman Mark¹

Affiliation:

1. Department of Medicinal Chemistry and Molecular Pharmacology, School of Pharmacy and Pharmaceutical Sciences, and the Purdue Cancer Center, Purdue University, West Lafayette, Indiana 47907, EntreMed, Inc., Rockville, Maryland 20850, and Department of Toxicology and Pharmacology, Ricera Biosciences, LLC, 7528 Auburn Road, Concord, Ohio 44077

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm070639e

Reference30 articles.

1. Biogenese von 2-Methoxy-oestradiol-(17?) in der menschlichen Leber

2. The excretion of five different 2-hydroxyoestrogen monomethyl ethers in human pregnancy urine

3. Aromatic Hydroxylation of Estrogens

4. The endogenous oestrogen metabolite 2-methoxyoestradiol inhibits angiogenesis and suppresses tumour growth

5. The cytotoxic effects of estradiol-17β, catecholestradiols and methoxyestradiols on dividing MCF-7 and Hela cells

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