First Computational Evidence for a Catalytic Bridging Hydroxide Ion in a Phosphodiesterase Active Site-Reference-Cited by-同舟云学术

First Computational Evidence for a Catalytic Bridging Hydroxide Ion in a Phosphodiesterase Active Site

Published:2001-03-01 Issue:12 Volume:123 Page:2835-2838
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Zhan Chang-Guo¹,Zheng Fang¹

Affiliation:

1. Contribution from the Department of Chemistry, Central China Normal University, Wuhan 430070, P. R. China, the Department of Medicine, College of Physicians & Surgeons, Columbia University, New York, New York 10032, and the Pacific Northwest National Laboratory, Mailstop K2-21, Battelle Blvd., P.O. Box 999, Richland, Washington 99352

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja005529a

Reference25 articles.

1. Purification and Properties of Periplasmic 3’:5’-Cyclic Nucleotide Phosphodiesterase

2. Hormonal Regulation of Cyclic Nucleotide Phosphodiesterases*

3. Phosphodiesterase (PDE)4 inhibitors: anti-inflammatory drugs of the future?

4. The Multienzyme PDE4 Cyclic Adenosine Monophosphate–Specific Phosphodiesterase Family: Intracellular Targeting, Regulation, and Selective Inhibition by Compounds Exerting Anti-inflammatory and Antidepressant Actions

5. A New Generation of Phosphodiesterase Inhibitors: Multiple Molecular Forms of Phosphodiesterase and the Potential for Drug Selectivity

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