Pharmacophore Modeling, Docking, and Principal Component Analysis Based Clustering: Combined Computer-Assisted Approaches To Identify New Inhibitors of the Human Rhinovirus Coat Protein-Reference-Cited by-同舟云学术

Pharmacophore Modeling, Docking, and Principal Component Analysis Based Clustering: Combined Computer-Assisted Approaches To Identify New Inhibitors of the Human Rhinovirus Coat Protein

Published:2005-09-02 Issue:20 Volume:48 Page:6250-6260
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Steindl Theodora M.¹,Crump Carolyn E.¹,Hayden Frederick G.¹,Langer Thierry¹

Affiliation:

1. Department of Pharmaceutical Chemistry, Institute of Pharmacy, and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innrain 52c, A-6020 Innsbruck, Austria, and Department of Internal Medicine, University of Virginia School of Medicine, Box 473, Charlottesville, Virginia 22908

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm050343d

Reference38 articles.

1. Analysis of three structurally related antiviral compounds in complex with human rhinovirus 16

2. Structural studies of two rhinovirus serotypes complexed with fragments of their cellular receptor

3. Efficacy and Safety of Oral Pleconaril for Treatment of Colds Due to Picornaviruses in Adults: Results of 2 Double-Blind, Randomized, Placebo-Controlled Trials

Cited by 43 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Computer-aided drug design in seeking viral capsid modulators;Drug Discovery Today;2023-06

2. Pharmacophore-based Screening for Identification of Human Acyl-CoA Cholesterol Acyltransferase Inhibitors: An In-silico Study;Letters in Drug Design & Discovery;2021-08

3. Molecular optimization, docking, and dynamic simulation profiling of selective aromatic phytochemical ligands in blocking the SARS-CoV-2 S protein attachment to ACE2 receptor: an in silico approach of targeted drug designing;Journal of Advanced Veterinary and Animal Research;2021

4. Comparing molecular dynamics-derived pharmacophore models with docking: A study on CDK-2 inhibitors;Chemical Data Collections;2020-08

5. Application of Computational Techniques to Unravel Structure-Function Relationship and their Role in Therapeutic Development;Current Topics in Medicinal Chemistry;2018-12-31