Inhibition of MIF Bioactivity by Rational Design of Pharmacological Inhibitors of MIF Tautomerase Activity
Author:
Affiliation:
1. The Picower Institute for Medical Research, Manhasset, New York 11030, Seattle Genetics Inc., 22215 26th Avenue, SE, Bothell, Washington 98021, and Department of Pharmacology, School of Medicine, Yale University, New Haven, Connecticut 06520
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm010534q
Reference32 articles.
1. MIF as a glucocorticoid-induced modulator of cytokine production
2. MIF is a pituitary-derived cytokine that potentiates lethal endotoxaemia
3. Targeted Disruption of Migration Inhibitory Factor Gene Reveals Its Critical Role in Sepsis
4. An essential role for macrophage migration inhibitory factor in the tuberculin delayed-type hypersensitivity reaction.
5. Involvement of macrophage migration inhibitory factor in the evolution of rat adjuvant arthritis
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