Secondary Amides of (R)-3,3,3-Trifluoro-2-hydroxy-2-methylpropionic Acid as Inhibitors of Pyruvate Dehydrogenase Kinase
Author:
Affiliation:
1. Novartis Institute for Biomedical Research, 556 Morris Avenue, Summit, New Jersey 07901
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm990358%2B
Reference75 articles.
1. Inactivation of pyruvate dehydrogenase complex in heart muscle mitochondria of gold-thioglucose-induced obese mice is not due to a stable increase in activity of pyruvate dehydrogenase kinase
2. Active and inactive forms of pyruvate dehydrogenase in rat heart and kidney: Effect of diabetes, fasting, and refeeding on pyruvate dehydrogenase interconversion
3. Effect of starvation and insulin in vivo on the activity of the pyruvate dehydrogenase complex in rat skeletal muscles
4. Short Term Regulation of Mouse Pyruvate Dehydrogenase Complex by Insulin
5. Lactate Production and Pyruvate Dehydrogenase Activity in Fat and Skeletal Muscle From Diabetic Rats
Cited by 70 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Recent advances in pyruvate dehydrogenase kinase inhibitors: Structures, inhibitory mechanisms and biological activities;Bioorganic Chemistry;2024-03
2. Tsuji–Trost Based Cascades: From Passerini Adducts of Cinnamaldehyde to Allylated Oxazolones;The Journal of Organic Chemistry;2024-01-12
3. Design, Synthesis, and Evaluation of Novel Pyruvate Dehydrogenase Kinase Inhibitors;Medicinal Chemistry;2023-03
4. Organocatalytic stereoselective cyanosilylation of small ketones;Nature;2022-05-04
5. Structure-based drug design of novel and highly potent pyruvate dehydrogenase kinase inhibitors;Bioorganic & Medicinal Chemistry;2021-12
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3