Improved Binding of Cytochrome P450cam Substrate Analogues Designed To Fill Extra Space in the Substrate Binding Pocket-Reference-Cited by-同舟云学术

Improved Binding of Cytochrome P450cam Substrate Analogues Designed To Fill Extra Space in the Substrate Binding Pocket

Published:1996-01-01 Issue:5 Volume:35 Page:1485-1499
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Helms Volkhard¹,Deprez Eric¹,Gill Edward¹,Barret Christel¹,Hui Bon Hoa Gaston¹,Wade Rebecca C.¹

Affiliation:

1. European Molecular Biology Laboratory, Meyerhofstrasse 1, 69012 Heidelberg, Germany, INSERM Unité 310, Institut de Biologie Physico-Chimique, 13, rue Pierre et Marie Curie, 75005 Paris, France, and Department of Pharmacology, University of Oxford, Oxford OX1 3QT, England

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/bi951817l

Reference98 articles.

1. Design of enzyme inhibitors using iterative protein crystallographic analysis

2. The roles of active site hydrogen bonding in cytochrome P-450cam as revealed by site-directed mutagenesis.

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