A New Structural Motif for the Design of Potent Glucosidase Inhibitors
Author:
Affiliation:
1. Department of Chemistry, Simon Fraser University 8888 University Drive, Burnaby British Columbia V5A 1S6, Canada
Publisher
American Chemical Society (ACS)
Subject
Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis
Link
https://pubs.acs.org/doi/pdf/10.1021/ja005746b
Reference23 articles.
1. Sugar-mimic glycosidase inhibitors: natural occurrence, biological activity and prospects for therapeutic application
2. Acarbose
3. Aminosugar derivatives as potential anti-human immunodeficiency virus agents.
4. STEREOCHEMISTRY AND THE MECHANISM OF ENZYMATIC REACTIONS
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