Design, Synthesis, and Biological Evaluation of Cytotoxic 11-Alkenylindenoisoquinoline Topoisomerase I Inhibitors and Indenoisoquinoline−Camptothecin Hybrids-Reference-Cited by-同舟云学术

Design, Synthesis, and Biological Evaluation of Cytotoxic 11-Alkenylindenoisoquinoline Topoisomerase I Inhibitors and Indenoisoquinoline−Camptothecin Hybrids

Published:2003-06-17 Issue:15 Volume:46 Page:3275-3282
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Fox Brian M.¹,Xiao Xiangshu¹,Antony Smitha¹,Kohlhagen Glenda¹,Pommier Yves¹,Staker Bart L.¹,Stewart Lance¹,Cushman Mark¹

Affiliation:

1. Department of Medicinal Chemistry and Molecular Pharmacology, School of Pharmacy and Pharmacal Sciences, Purdue University, West Lafayette, Indiana 47907, Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892-4255, and BioStructures Group, deCODE genetics, Inc., 7869 N.E. Day Road, Bainbridge Island, Washington 98110

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0300476

Reference22 articles.

1. Protein-Linked DNA Strand Breaks Induced by NSC 314622, a Novel Noncamptothecin Topoisomerase I Poison

2. Synthesis of Cytotoxic Indenoisoquinoline Topoisomerase I Poisons

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