New Poly(ADP-ribose) Polymerase-1 Inhibitors with Antioxidant Activity Based on 4-Carboxamidobenzimidazole-2-ylpyrroline and -tetrahydropyridine Nitroxides and Their Precursors-Reference-Cited by-同舟云学术

New Poly(ADP-ribose) Polymerase-1 Inhibitors with Antioxidant Activity Based on 4-Carboxamidobenzimidazole-2-ylpyrroline and -tetrahydropyridine Nitroxides and Their Precursors

Published:2009-02-26 Issue:6 Volume:52 Page:1619-1629
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Kálai Tamás¹,Balog Mária¹,Szabó Alíz¹,Gulyás Gergely¹,Jekő József¹,Sümegi Balázs¹,Hideg Kálmán¹

Affiliation:

1. Department of Organic and Medicinal Chemistry and Department of Biochemistry and Medical Chemistry, University of Pécs, H-7624 Pécs, Szigeti str. 12, Hungary, and Department of Chemistry, College of Nyíregyháza, 4440 Nyíregyháza, Sóstói str. 31/B, Hungary

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm801476y

Reference54 articles.

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2. Potential clinical applications of poly(ADP-ribose) polymerase (PARP) inhibitors

3. Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia

4. The neuroprotective effect of cerebral poly(ADP-ribose)polymerase inhibition in a rat model of global ischemia

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