Discovery of Selective and Potent Inhibitors of Gram-Positive Bacterial Thymidylate Kinase (TMK)-Reference-Cited by-同舟云学术

Discovery of Selective and Potent Inhibitors of Gram-Positive Bacterial Thymidylate Kinase (TMK)

Published:2012-10-24 Issue:22 Volume:55 Page:10010-10021
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Martínez-Botella Gabriel¹,Breen John N.¹²,Duffy James E. S.³,Dumas Jacques¹,Geng Bolin¹,Gowers Ian K.³,Green Oluyinka M.¹,Guler Satenig¹,Hentemann Martin F.¹,Hernandez-Juan Felix A.³,Joseph-McCarthy Diane¹,Kawatkar Sameer¹,Larsen Nicholas A.²,Lazari Ovadia³,Loch James T.¹,Macritchie Jacqueline A.³,McKenzie Andrew R.¹,Newman Joseph V.¹,Olivier Nelson B.²,Otterson Linda G.¹,Owens Andrew P.³,Read Jon²,Sheppard David W.³,Keating Thomas A.¹

Affiliation:

1. AstraZeneca Infection Innovative Medicines, 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States

2. AstraZeneca Discovery Sciences, 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States

3. BioFocus, Chesterford Research Park, Saffron Walden CB10 1XL, U.K.

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm3011806

Reference21 articles.

1. Challenges of Antibacterial Discovery