Pharmacophore-Based Design of HIV-1 Integrase Strand-Transfer Inhibitors
Author:
Affiliation:
1. Dipartimento Farmaco-Chimico, Università di Messina, Viale Annunziata, 98168 Messina, Italy, and Molecular Medicine, Katholieke Universiteit Leuven and IRC KULAK, Kapucijnenvoer 33, B-3000 Leuven, Flanders, Belgium
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm050549e
Reference23 articles.
1. Action of Anti-HIV Drugs and Resistance: Reverse Transcriptase Inhibitors and Protease Inhibitors
2. HIV-1 Integrase: A Target for New AIDS Chemotherapeutics
3. HIV-1 Integrase Inhibitors: A Decade of Research and Two Drugs in Clinical Trial
4. Inhibitors of Strand Transfer That Prevent Integration and Inhibit HIV-1 Replication in Cells
5. Diketo acid inhibitor mechanism and HIV-1 integrase: Implications for metal binding in the active site of phosphotransferase enzymes
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