A Peptide Nucleic Acid−Neamine Conjugate That Targets and Cleaves HIV-1 TAR RNA Inhibits Viral Replication-Reference-Cited by-同舟云学术

A Peptide Nucleic Acid−Neamine Conjugate That Targets and Cleaves HIV-1 TAR RNA Inhibits Viral Replication

Published:2004-08-28 Issue:20 Volume:47 Page:4806-4809
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Riguet Emmanuel¹,Tripathi Snehlata¹,Chaubey Binay¹,Désiré Jérôme¹,Pandey Virendra N.¹,Décout Jean-Luc¹

Affiliation:

1. Laboratoire de Chimie Bio-Organique, Département de Pharmacochimie Moléculaire, UMR 5063 CNRS/Université Joseph Fourier-Grenoble I, FR CNRS 2607, BP 138, 5 Avenue de Verdun, F-38243 Meylan, France, and Center for the Study of Emerging and Reemerging Pathogens, Department of Biochemistry and Molecular Biology, UMDNJ-New Jersey Medical School, 185 South Orange Avenue, Newark, New Jersey 07103

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm049642d

Reference40 articles.

1. Progress in Antisense Oligonucleotide Therapeutics

2. Modified (PNA, 2'-O-methyl and phosphoramidate) anti-TAR antisense oligonucleotides as strong and specific inhibitors of in vitro HIV-1 reverse transcription

3. Inhibition of HIV-1 ReplicationIn Vitroand in Human Infected Cells by Modified Antisense Oligonucleotides Targeting the tRNALys3/RNA Initiation Complex

4. Sequence-Selective Recognition of DNA by Strand Displacement with a Thymine-Substituted Polyamide

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