Triplex-forming peptide nucleic acids as emerging ligands to modulate structure and function of complex RNAs-Reference-Cited by-同舟云学术

Triplex-forming peptide nucleic acids as emerging ligands to modulate structure and function of complex RNAs

Published:2024 Issue:15 Volume:60 Page:1999-2008
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Katkevics Martins¹^ORCID,MacKay James A.²^ORCID,Rozners Eriks³^ORCID

Affiliation:

1. Latvian Institute of Organic Synthesis, Aizkraukles 21, Riga, LV-1006, Latvia

2. Department of Chemistry and Biochemistry, Elizabethtown College, Elizabethtown, PA 17022, USA

3. Department of Chemistry, Binghamton University, Binghamton, NY 13902, USA

Abstract

Over the last three decades, triplex-forming PNAs have emerged as ligands for the recognition of double-stranded RNA. Strong and sequence selective binding using synthetic nucleobases offers opportunity for modulation of biological function of endogenous RNA transcripts.

Funder

National Institutes of Health

National Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/CC/D3CC05409H

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