Structural Differences of Matrix Metalloproteinases with Potential Implications for Inhibitor Selectivity Examined by the GRID/CPCA Approach-Reference-Cited by-同舟云学术

Structural Differences of Matrix Metalloproteinases with Potential Implications for Inhibitor Selectivity Examined by the GRID/CPCA Approach

Published:2002-05-16 Issue:13 Volume:45 Page:2675-2684
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Terp Gitte Elgaard¹,Cruciani Gabriele¹,Christensen Inge Thøger¹,Jørgensen Flemming Steen¹

Affiliation:

1. Department of Medicinal Chemistry, Royal Danish School of Pharmacy, Universitetsparken 2, DK-2100 Copenhagen, Denmark, Laboratory for Chemometrics, University of Perugia, Via Elce di Sotto 10, I-06123 Perugia, Italy, and Novo Nordisk A/S, Novo Nordisk Park, DK-2760 Måløv, Denmark

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0109053

Reference55 articles.

1. Matrix metalloproteinase degradation of extracellular matrix: biological consequences

2. ER-to-Golgi transport visualized in living cells

3. Crystal structure of the complex formed by the membrane type 1-matrix metalloproteinase with the tissue inhibitor of metalloproteinases-2, the soluble progelatinase A receptor

4. High Resolution Structure of the N-terminal Domain of Tissue Inhibitor of Metalloproteinases-2 and Characterization of Its Interaction Site with Matrix Metalloproteinase-3

5. Three-dimensional structure of human tissue inhibitor of metalloproteinases-2 at 2.1 Å resolution

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