Targeting the Ribose and Phosphate Binding Site of p38 Mitogen-Activated Protein (MAP) Kinase: Synthesis and Biological Testing of 2-Alkylsulfanyl-, 4(5)-Aryl-, 5(4)-Heteroaryl-Substituted Imidazoles-Reference-Cited by-同舟云学术

Targeting the Ribose and Phosphate Binding Site of p38 Mitogen-Activated Protein (MAP) Kinase: Synthesis and Biological Testing of 2-Alkylsulfanyl-, 4(5)-Aryl-, 5(4)-Heteroaryl-Substituted Imidazoles

Published:2008-09-03 Issue:18 Volume:51 Page:5630-5640
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Koch Pierre¹,Bäuerlein Christiane¹,Jank Hartmut¹,Laufer Stefan¹

Affiliation:

1. Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmacy, Eberhard-Karls University of Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm800373t

Reference24 articles.

1. Rheumatoid Arthritis

2. p38 Mitogen-Activated Protein Kinase Inhibitors— Mechanisms and Therapeutic Potentials

3. p38 MAP kinases: key signalling molecules as therapeutic targets for inflammatory diseases

4. A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

5. MAP Kinase p38Inhibitors: Clinical Results and an Intimate Look at Their Interactions with p38α Protein

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