Diamino Benzo[b]thiophene Derivatives as a Novel Class of Active Site Directed Thrombin Inhibitors. 5. Potency, Efficacy, and Pharmacokinetic Properties of Modified C-3 Side Chain Derivatives

Author:

Sall Daniel J.1,Bailey Dianna L.1,Bastian Jolie A.1,Buben John A.1,Chirgadze Nickolay Y.1,Clemens-Smith Amy C.1,Denney Michael L.1,Fisher Matthew J.1,Giera Deborah D.1,Gifford-Moore Donetta S.1,Harper Richard W.1,Johnson Lea M.1,Klimkowski Valentine J.1,Kohn Todd J.1,Lin Ho-Shen1,McCowan Jefferson R.1,Palkowitz Alan D.1,Richett Michael E.1,Smith Gerald F.1,Snyder David W.1,Takeuchi Kumiko1,Toth John E.1,Zhang Minsheng1

Affiliation:

1. Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana 46285

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Reference26 articles.

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