Synthesis and Physicochemical Characterization of Gd-C4-Thyroxin-DTPA, a Potential MRI Contrast Agent. Evaluation of Its Affinity for Human Serum Albumin by Proton Relaxometry, NMR Diffusometry, and Electrospray Mass Spectrometry

Author:

Henoumont C.1,Vander Elst L.1,Laurent S.1,Muller R. N.1

Affiliation:

1. Department of General, Organic and Biomedical Chemistry, NMR and Molecular Imaging Laboratory, University of Mons, 19 avenue Maistriau, B-7000 Mons, Belgium

Publisher

American Chemical Society (ACS)

Subject

Materials Chemistry,Surfaces, Coatings and Films,Physical and Theoretical Chemistry

Reference47 articles.

1. Muller, R. N.InEncyclopedia of Nuclear Magnetic Resonance;Grant, D. M., Harris, R. K., Eds.Wiley and Sons:New York, 1996; pp1438−1444.

2. Gadolinium(iii) complexes as MRI contrast agents: ligand design and properties of the complexes

3. Classification and basic properties of contrast agents for magnetic resonance imaging

4. Toth, E.; Helm, L.; Merbach, A. E.InThe chemistry of contrast agents in medical magnetic resonance imaging;Merbach, A. E.; Toth, E., Eds.Wiley and Sons:New York, 2001; pp45−119.

5. In vitro Relaxometric and Luminescence Characterization of P792 (Gadomelitol, Vistarem ® ), an Efficient and Rapid Clearance Blood Pool MRI Contrast Agent

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