Surface engineering of silica nanoparticles with a gadolinium–PCTA complex for efficient T1-weighted MRI contrast agents-Reference-Cited by-同舟云学术

Surface engineering of silica nanoparticles with a gadolinium–PCTA complex for efficient T1-weighted MRI contrast agents

Published:2020 Issue:41 Volume:44 Page:18031-18047
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Mathieu Paul¹²³⁴⁵,Chalet Marie¹⁶⁷⁸⁴,Clain Marie Myriam¹⁶⁷⁸⁴,Teulon Lauryanne¹²³⁴⁵,Benoist Eric¹⁶⁷⁸⁴,Leygue Nadine¹⁶⁷⁸⁴,Picard Claude¹⁶⁷⁸⁴^ORCID,Boutry Sébastien⁹¹⁰¹¹¹²¹³,Laurent Sophie⁹¹⁰¹¹¹²¹³^ORCID,Stanicki Dimitri⁹¹⁰¹¹¹²¹³,Hénoumont Céline⁹¹⁰¹¹¹²¹³,Novio Fernando¹⁴¹⁵¹⁶¹⁷^ORCID,Lorenzo Julia¹⁸¹⁹²⁰²¹¹⁷^ORCID,Montpeyó David¹⁸¹⁹²⁰²¹¹⁷,Ciuculescu-Pradines Diana¹²³⁴⁵^ORCID,Amiens Catherine¹²³⁴⁵^ORCID

Affiliation:

1. CNRS

2. LCC (Laboratoire de Chimie de Coordination)

3. F-31077 Toulouse Cedex 4

4. France

5. Université de Toulouse

6. Laboratoire de Synthèse et Physico-Chimie de Molécules d'Intérêt Biologique (SPCMIB)

7. UMR-5068

8. 31062 Toulouse Cedex 9

9. Department of General

10. Organic and Biomedical Chemistry

11. NMR and Molecular Imaging Laboratory

12. University of Mons

13. B-7000 Mons

14. Departament de Química

15. Universitat Autònoma de Barcelona (UAB)

16. 08193 Cerdanyola del Vallès

17. Spain

18. Institut de Biotecnologia i Biomedicina

19. Departament de Bioquímica i de Biologia Molecular

20. Universitat Autònoma de Barcelona

21. 08193 Bellaterra

Abstract

Covalent grafting of diaqua Gd(iii)-complexes onto dense silica nanoparticles affords non-toxic contrast agents suitable for high field MRI pre-clinical studies.

Funder

European Regional Development Fund

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2020/NJ/D0NJ04430J

Reference55 articles.

1. Engineering of inorganic nanoparticles as magnetic resonance imaging contrast agents

2. Strategies for increasing the sensitivity of gadolinium based MRI contrast agents

3. Influence of molecular parameters and increasing magnetic field strength on relaxivity of gadolinium- and manganese-based T1contrast agents

4. Partial least squares algorithms and methods

5. Chemistry of MRI Contrast Agents: Current Challenges and New Frontiers

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