Biselectivity of isoDGR Peptides for Fibronectin Binding Integrin Subtypes α5β1 and αvβ6: Conformational Control through Flanking Amino Acids-Reference-Cited by-同舟云学术

Biselectivity of isoDGR Peptides for Fibronectin Binding Integrin Subtypes α5β1 and αvβ6: Conformational Control through Flanking Amino Acids

Published:2013-02-18 Issue:4 Volume:56 Page:1509-1519
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Bochen Alexander¹,Marelli Udaya Kiran¹,Otto Elke¹,Pallarola Diego²,Mas-Moruno Carlos¹,Di Leva Francesco Saverio³,Boehm Heike²,Spatz Joachim P.²,Novellino Ettore⁴,Kessler Horst¹⁵,Marinelli Luciana⁴

Affiliation:

1. Institute for Advanced Study and Center of Integrated Protein Science, Department Chemie, Technische Universität München, Lichtenbergstrasse 4, 85747 Garching, Germany

2. Department of New Materials and Biosystems, Max Planck Institute for Intelligent Systems, Heisenbergstrasse 3, 70569 Stuttgart, Germany & Department of Biophysical Chemistry, University of Heidelberg, INF 253, 69120 Heidelberg, Germany

3. Department of Drug Discovery and Development, Istituto Italiano di Tecnologia (IIT), Via Morego 30, 16163 Genova, Italy

4. Dipartimento di Chimica Farmaceutica e Tossicologica, Università di Napoli “Federico II”, Via D. Montesano 49, 80131 Napoli, Italy

5. Chemistry Department, Faculty of Science, King Abdulaziz University, P.O. Box 80203, Jeddah 21589, Saudi Arabia

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm301221x

Reference76 articles.

1. Integrin ligands at a glance

2. Targeting RGD Recognizing Integrins: Drug Development, Biomaterial Research, Tumor Imaging and Targeting