Stabilization of a Native Protein Mediated by Ligand Binding Inhibits Amyloid Formation Independently of the Aggregation Pathway
Author:
Affiliation:
1. Dipartimento di Scienze Biochimiche, Università di Firenze, Viale Morgagni 50, 50134 Firenze, Italy
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm0606488
Reference43 articles.
1. Folding proteins in fatal ways
2. Molecular Mechanisms of Amyloidosis
3. Protein Misfolding, Functional Amyloid, and Human Disease
4. The binding of thioflavin-T to amyloid fibrils: localisation and implications
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