Structure-Based Design of Substituted Diphenyl Sulfones and Sulfoxides as Lipophilic Inhibitors of Thymidylate Synthase
Author:
Affiliation:
1. Agouron Pharmaceuticals, Inc., 3565 General Atomics Court, San Diego, California 92121
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm960613f
Reference13 articles.
1. Design of enzyme inhibitors using iterative protein crystallographic analysis
2. Structure-Based Design of Lipophilic Quinazoline Inhibitors of Thymidylate Synthase
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4. Biosynthetic origin of the carbon skeleton and oxygen atoms of nargenicin A1
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