A New Avenue to Diversity‐Oriented Synthesis of Diaryl Sulfones

Author:

Verma Narsingh1,Vikram Singh Ravindra2,Singh Raghuvanshi Dushyant12ORCID

Affiliation:

1. Phytochemistry Division CSIR-Central Institute of Medicinal and Aromatic Plants Lucknow 226015 India

2. R&D, Technology, and Innovation Merck-Life Science, Jigani Bangalore 560100 India

Abstract

AbstractWe describe a highly efficient route for the sulfonylation (C‐SO2) of various halo arenes, boronic acids, and aromatic diazonium salt through a cross‐coupling reaction. The protocol incorporates the efficient use of Cu(OAc)2/K2CO3 and N‐Hydoxy aryl sulfonamide as an aryl sulfone surrogate. Various substrates and functional groups were well tolerated in this reaction system.

Publisher

Wiley

Subject

General Chemistry

Reference84 articles.

1.  

2. R. J. Cremlyn An Introduction to Organosulfur Chemistry; John Wiley and Sons: Chichester UK 1996;

3. Thiosulfonates as Emerging Reactants: Synthesis and Applications

4. Sulfur Containing Scaffolds in Drugs: Synthesis and Application in Medicinal Chemistry

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