Synthesis of Analogs of 2-Methoxyestradiol with Enhanced Inhibitory Effects on Tubulin Polymerization and Cancer Cell Growth-Reference-Cited by-同舟云学术

Synthesis of Analogs of 2-Methoxyestradiol with Enhanced Inhibitory Effects on Tubulin Polymerization and Cancer Cell Growth

Published:1997-07-01 Issue:15 Volume:40 Page:2323-2334
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Cushman Mark¹,He Hu-Ming¹,Katzenellenbogen John A.¹,Varma Ravi K.¹,Hamel Ernest¹,Lin Chii M.¹,Ram Siya¹,Sachdeva Yesh P.¹

Affiliation:

1. Department of Medicinal Chemistry and Molecular Pharmacology, School of Pharmacy and Pharmacal Sciences, Purdue University, West Lafayette, Indiana 47907, Department of Chemistry, University of Illinois, Urbana, Illinois 61801, Drug Synthesis and Chemistry Branch, Developmental Therapeutics Program, Division of Cancer Treatment, Diagnosis and Centers, National Cancer Institute, Executive Plaza North, Suite 831, 6130 Executive Boulevard, Rockville, Maryland 20852, Laboratory of Drug Discovery Research and...

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm9700833

Reference46 articles.

1. The excretion of five different 2-hydroxyoestrogen monomethyl ethers in human pregnancy urine

2. The cytotoxic effects of estradiol-17β, catecholestradiols and methoxyestradiols on dividing MCF-7 and Hela cells

Cited by 84 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Flash vacuum pyrolysis of steroid propargyl ethers;Journal of Analytical and Applied Pyrolysis;2024-08

2. Advances in the Synthesis of Mono/Di/Polyfluoroalkyl Ethers;Chinese Journal of Organic Chemistry;2024

3. The Structural Diversity and Biological Activity of Steroid Oximes;Molecules;2023-02-10

4. Triazole-based estradiol dimers prepared via CuAAC from 17α-ethinyl estradiol with five-atom linkers causing G2/M arrest and tubulin inhibition;Bioorganic Chemistry;2023-02

5. Cell Fate following Irradiation of MDA-MB-231 and MCF-7 Breast Cancer Cells Pre-Exposed to the Tetrahydroisoquinoline Sulfamate Microtubule Disruptor STX3451;Molecules;2022-06-14